Platelet Function and Coagulability during Cardiopulmonary Bypass in Children: Analysis by Sonoclot with a Heparinase Glass-Beads Cuvette
[2003 SPA/JSPA Joint Meeting SR16] Platelet Function and Coagulability during Cardiopulmonary Bypass in Children: Analysis by Sonoclot with a Heparinase Glass-Beads Cuvette. Y. Toyoshima, A. Kimura, M. Nawa, S. Kawana Departments of Anesthesiology, Hokkaido Children’s Hospital and Medical Center Introduction : It has been difficult to evaluate platelet function during cardiopulmonary bypass (CPB) due to the effect of heparin. Sonoclot analysis with a heparinase glass-beads cuvette enables bedside monitoring of platelet function and coagulability in heparinized blood. In this preliminary study, we measured platelet function and coagulability during CPB in children with congenital heart disease (CHD). Methods : Approval for the study was obtained from our institutions review board, and informed consent was obtained from the parents of the children. The subjects were five children with CHD (1.2-4.5 yrs old) who were scheduled to undergo cardiac surgery under CPB. Bloo