Sonoclot Analyzer, ACT Machine India, Thromboelastography, Cardiac Surgery, Liver Transplant

CHENNAI: A team of surgeons from a private hospital in the city crossed another milestone, performing five transplants simultaneously in a marathon session of 12 hours recently.  Doctors from Global Hospitals transplanted two kidneys and three lobes of liver to five people at one go. While four patients benefited from a deceased donor, one patient received a part of liver from a living donor. "This is also the first time we have successfully performed a split liver surgery and transplanted it in two adults against the norm of giving it to an adult and a child," said liver transplant surgeon Dr Mohammed Rela.  Ten days ago, a liver transplant team consisting of 11 surgeons and a kidney transplant team with seven surgeons started work. Doctors harvested two kidneys, a liver, heart and lungs from a middle-aged donor. "He had health complications and also suffered from mild renal dysfunction. We withheld one kidney for an inpatient transplant and put the other kidney in...

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After nearly four years of wait, catheterization laboratory or cath lab was delivered at Bhopal memorial hospital and research centre (BMHRC). The new machine would be operational within a month and would be used to perform cardiac and non-cardiac vascular interventions in the gas victims' hospital. Top-of-the-line clinic with diagnostic imaging equipment, which cost Rs 5.21 crore, would be used to perform assessment of total heart function including pediatric congenital heart defects. "Arrival of the cath lab, marks a positive change for the gas victims hospital. We are in the process of upgrading most of our equipment," said BMHRC director Dr Manoj Pandey. For more information on Sonoclot ACT Machine,  please follow: www.lifediagnostica.com

Background: Pediatric cardiac surgery patients are at high risk for bleeding, and the antifibrinolytic drug tranexamic acid (TA) is often used to reduce blood loss. However, dosing schemes remain empirical as a consequence of the absence of pharmacokinetic study in this population. The authors’ objectives were thus to investigate the population pharmacokinetics of TA in pediatric cardiac surgery patients during cardiopulmonary bypass (CPB).   Methods: Twenty-one patients were randomized to receive TA either continuously (10 mg/kg followed by an infusion of 1 mg·kg −1 ·h −1  throughout the operation, and 10 mg/kg into the CPB) or discontinuously (10 mg/kg, then 10 mg/kg into the CPB and 10 mg·kg −1 ·h −1  at the end of CPB). Serum concentrations were measured at eight time points with chromatography–mass spectrometry and the data were modeled using Monolix (Lixoft, Orsay, France).  Results: Tranexamic acid pharmacokinetics was ascribed to a two-compartment open m...

A comatose Pune woman with a sudden and total liver failure got a new lease of life thanks to her son who promptly donated his liver. The operation was successful and both mother and son are recuperating at home after having been discharged from hospital, doctors said. Gunwanti Gundesha, 49, was brought to the Global Hospital at Parel here a month ago (May 29), virtually in a dying state with her vital organ (liver) having completely failed. Global Hospital's medical team comprising doctors Hemant Vadeyar and Samir Shah immediately put Gunwanti on a ventilator and conducted other tests which confirmed the worst -- her liver had irreparably collapsed and she was sinking fast. "The patient's condition was bad due to brain swelling, which is a terminal stage in liver failure. The challenge was huge as we had to perform the operation on a very unstable patient and the donor operation also had to be completed simultaneously with the same urgency," said Prof. Mohamed...

Chethana (name changed), 10, had a virtual rebirth on Friday when she underwent a bile duct enlargement correction surgery at the newly-launched Liver Clinic here. The nation's first government-owned liver clinic offers a glimmer of hope for thousands of chronic liver disorder patients. The north Karnataka girl was among six persons who underwent surgeries at a surgical gastroenterology workshop. The operations, which were done at the Victoria Hospital premises, were beamed live to the inauguration venue. The Liver Clinic, run by the department of gastroenterology, Bangalore Medical College and Research Institute (BMCRI), offers to conduct liver transplants on poor patients for Rs 5 lakh as against Rs 40 lakh charged by corporate hospitals. The state government has sanctioned Rs 7.5 crore for the clinic. As many as 150 patients with various liver disorders have been awaiting transplant and have registered with the Zonal Coordination Committee for Organ Tran...

Brave Dhruvika has finally won the battle against deadly Citrullinemia with the help of his grandmother. Dhruvika was diagnosed with Citrullinemia just after her birth. Now she has been gifted a new life with a liver transplant,the liver was donated by her grandmother. Now Dhruvika has become the youngest in the country to fight Citrullinemia with a liver transplant. Citrullinemia is an autosomal recessive urea cycle disorder that causes ammonia and other toxic substances to accumulate in the blood. Since the substances also accumulate in the urine, the disorder can also be called citrullinuria. It is  a life-threatening disease in which the proteins do not get broken because of the deficiency of an enzyme. In such circumstances, the levels of ammonia become very high. Ammonia is one product that can cross the blood brain barrier, causing the brain cells to swell up and leading to other grave problems too. Dhruvika was born on February 8, 2013 at Cloud Nine Hospital in B...

Valley View Hospital is the only place in the region where patients and doctors can reap the benefits of robotic angioplasty. It was the eighth hospital in the nation to use the technology, and it now is one of only 14 nationwide. The Corindus CorPath Vascular Robotic system occupies the same room in Valley View’s Heart & Vascular Center where interventional angioplasty used to be performed manually. And the fundamentals of the procedure — which entails guiding a tiny balloon, often surrounded by a metal mesh stent, into a patient’s clogged artery and inflating it to open the blockage — remain the same. But the robot adds a level of precision that some hope will make it the new standard of care. “The utility of the robot ... is a safety issue and a cost issue,” said Dr. Frank Laws, medical director of the Heart & Vascular Center. He explained that using the robot results in less radiation exposure to patient and physician. It also results in cost savings of 20 to 30 pe...

Comparison of Sonoclot with Thromboelastography TEG in Liver Transplant Sample I: Sonoclot showed that the patient is having Platelet Dysfunction. Total Testing Time for Sonoclot: 18 mins for Thromboelastography TEG: 112 mins and it showed Factor deficiency Sample II: Sonoclot showed that the patient is having Platelet Dysfunction. Total Testing Time for Sonoclot: 18 mins for Thromboelastography TEG: 55 mins and it showed Factor deficiency Sample III: Sonoclot showed that the patient is having Platelet Dysfunction. Total Testing Time for Sonoclot: 18 mins for Thromboelastography TEG: 48 mins and for the first time it showed Platelet Dysfunction Sample IV: Sonoclot showed that the patient is having Platelet Dysfunction. Total Testing Time for Sonoclot: 19 mins for Thromboelastography TEG: 67 mins and it confirmed Sonoclot analysis of Platelet Dysfunction Sample V:  Sonoclot showed that the patient is having Platelet Dysfunction. Total Te...

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