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Showing posts from February, 2021

Appropriate Dosage Of Unfraction Heparin And Low Molecular Weight Heparin In Hemodialysis Patients

Appropriate Dosage Of Unfraction Heparin And Low Molecular Weight Heparin In Hemodialysis Patients [Article in Chinese] Xiao Q, Sun XF, Zhang D, Ma ZF, Wu MG, Wang H, Chen XM. Institute of Nephrology, General Hospital of Chinese People's Liberation Army, Beijing 100853, China.   Abstract OBJECTIVE: To investigate the appropriate dose of unfraction heparin and low molecular weight heparin (LMWH) in hemodialysis patients.   METHODS: Thirty-eight hemodialysis patients were enrolled and randomly allocated into four groups.The initial bolus dose for the Low-dose (LH, n = 10) and high-dose heparin (HH, n = 10) groups were 35 U/kg and 55 U/kg, respectively.The repeated maintenance dose for both groups were 10 U/kg.h and 16 U/kg.h, respectively. Fragmin were administered as single bolus (60 U/kg or 80 U/kg) at 30 minutes before hemodialysis in Low-dose LMWH(LLMWH, n = 10) and High-dose LMWH (HLMW, n = 8) group, respectively. Furthermore, the dialysis circuits in LUFH and LLMWUF