Sonoclot Analyzer, ACT Machine India, Thromboelastography, Cardiac Surgery, Liver Transplant

A comatose Pune woman with a sudden and total liver failure got a new lease of life thanks to her son who promptly donated his liver. The operation was successful and both mother and son are recuperating at home after having been discharged from hospital, doctors said. Gunwanti Gundesha, 49, was brought to the Global Hospital at Parel here a month ago (May 29), virtually in a dying state with her vital organ (liver) having completely failed. Global Hospital's medical team comprising doctors Hemant Vadeyar and Samir Shah immediately put Gunwanti on a ventilator and conducted other tests which confirmed the worst -- her liver had irreparably collapsed and she was sinking fast. "The patient's condition was bad due to brain swelling, which is a terminal stage in liver failure. The challenge was huge as we had to perform the operation on a very unstable patient and the donor operation also had to be completed simultaneously with the same urgency," said Prof. Mohamed...

Chethana (name changed), 10, had a virtual rebirth on Friday when she underwent a bile duct enlargement correction surgery at the newly-launched Liver Clinic here. The nation's first government-owned liver clinic offers a glimmer of hope for thousands of chronic liver disorder patients. The north Karnataka girl was among six persons who underwent surgeries at a surgical gastroenterology workshop. The operations, which were done at the Victoria Hospital premises, were beamed live to the inauguration venue. The Liver Clinic, run by the department of gastroenterology, Bangalore Medical College and Research Institute (BMCRI), offers to conduct liver transplants on poor patients for Rs 5 lakh as against Rs 40 lakh charged by corporate hospitals. The state government has sanctioned Rs 7.5 crore for the clinic. As many as 150 patients with various liver disorders have been awaiting transplant and have registered with the Zonal Coordination Committee for Organ Tran...

Brave Dhruvika has finally won the battle against deadly Citrullinemia with the help of his grandmother. Dhruvika was diagnosed with Citrullinemia just after her birth. Now she has been gifted a new life with a liver transplant,the liver was donated by her grandmother. Now Dhruvika has become the youngest in the country to fight Citrullinemia with a liver transplant. Citrullinemia is an autosomal recessive urea cycle disorder that causes ammonia and other toxic substances to accumulate in the blood. Since the substances also accumulate in the urine, the disorder can also be called citrullinuria. It is  a life-threatening disease in which the proteins do not get broken because of the deficiency of an enzyme. In such circumstances, the levels of ammonia become very high. Ammonia is one product that can cross the blood brain barrier, causing the brain cells to swell up and leading to other grave problems too. Dhruvika was born on February 8, 2013 at Cloud Nine Hospital in B...

Valley View Hospital is the only place in the region where patients and doctors can reap the benefits of robotic angioplasty. It was the eighth hospital in the nation to use the technology, and it now is one of only 14 nationwide. The Corindus CorPath Vascular Robotic system occupies the same room in Valley View’s Heart & Vascular Center where interventional angioplasty used to be performed manually. And the fundamentals of the procedure — which entails guiding a tiny balloon, often surrounded by a metal mesh stent, into a patient’s clogged artery and inflating it to open the blockage — remain the same. But the robot adds a level of precision that some hope will make it the new standard of care. “The utility of the robot ... is a safety issue and a cost issue,” said Dr. Frank Laws, medical director of the Heart & Vascular Center. He explained that using the robot results in less radiation exposure to patient and physician. It also results in cost savings of 20 to 30 pe...

Comparison of Sonoclot with Thromboelastography TEG in Liver Transplant Sample I: Sonoclot showed that the patient is having Platelet Dysfunction. Total Testing Time for Sonoclot: 18 mins for Thromboelastography TEG: 112 mins and it showed Factor deficiency Sample II: Sonoclot showed that the patient is having Platelet Dysfunction. Total Testing Time for Sonoclot: 18 mins for Thromboelastography TEG: 55 mins and it showed Factor deficiency Sample III: Sonoclot showed that the patient is having Platelet Dysfunction. Total Testing Time for Sonoclot: 18 mins for Thromboelastography TEG: 48 mins and for the first time it showed Platelet Dysfunction Sample IV: Sonoclot showed that the patient is having Platelet Dysfunction. Total Testing Time for Sonoclot: 19 mins for Thromboelastography TEG: 67 mins and it confirmed Sonoclot analysis of Platelet Dysfunction Sample V:  Sonoclot showed that the patient is having Platelet Dysfunction. Total Te...

Platelet Function Absent For More Information Please Visit:  http://www.lifediagnostica.com/sonoclot

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http://www.ctsnet.org/events/sts-50th-annual-meeting-stsaats-tech-con-2014

In a rare case, a 10-year-old boy suffering from liver failure got a fresh lease of life after doctors innovatively transplanted a portion of his mother's liver into him. This was not a standard transplant as the mother was found to be unfit for donation due to an aberrant anomaly in her hepatic vein. But with the boy's liver condition deteriorating rapidly, an urgent liver transplant was advised to increase his chances of survival. Incidentally, only the mother's blood group matched with the patient's group. With no options left, the surgeons at Global Hospital came up with innovative means of both extracting the liver from the donor and also implanting into the recipient with minimum risk. "The mother's left portion of the liver was implanted into the child and the right hepatic vein of the child was used to reconstruct the middle vein," said Dr Thomas Cherian, liver transplant surgeon of the hospital, who performed the surgery. Both the mother...

  Title: Sonoclot Signature Analysis In Patients with Liver Disease And Its Correlation With Conventional Coagulation Studies. Running title: Sonoclot analysis in liver disease and correlation with conventional parameters Priyanka Saxena 1 , Chhagan Bihari 1 , Archana Rastogi 2 , Savita Agarwal 2 , Lovkesh Anand 3 and Shiv Kumar Sarin 3 Department of Hematology 1 , Department of Pathology 2 Department of Hepatology 3 Institute of Liver and Biliary Sciences D-1, Vasant Kunj, New Delhi-110070, India Word Count: 3498 Number of Figures: 4 Number of Tables: 4 Conflict of Interest: None Grants and Funds: None Applicable Address for Correspondence Dr. Chhagan Bihari Assistant Professor, Department of Hematology Institute of Liver and Biliary Sciences D-1, Vasant Kunj New Delhi-110070 Email: drcbsharma@gmail.com Contact No: +911146300000 (6035)   Abstract Introduction: Patients with liver disease have complex hemostatic defects leading to a de...

Wishing You and Your Family a Very Happy & Prosperous Diwali. Life Diagnostica www.lifediagnostica.com Sonoclot - Functional Hemostasis Management ACT Machine India

Sonoclot (SC1) ACT Machine incorporates Sonoclot's Proprietary Visco-Elastic technology and is extremely sensitive to the developing clot. Normal ACT Machines mechanically detect mature clot to report Activated Clotting Time which takes into account cumulative activity of Factors, Fibrin gel & Platelets to form a mature clot. On the other hand Sonoclot ACT Machine starts monitoring the viscosity changes, which is the first component to change when the coagulation cascade is triggered by the respective activators. Factor Xa triggers Prothrombin to Thrombin (Factor IIa) the sample is still in the liquid phase. As Thrombin forms it triggers Fibrinogen to Fibrin Polymerization the sample starts to gel and the viscosity starts increasing. Sonoclot ACT Machine is very sensitive to this changing viscosity and first reports ACT, which is a function of Factor Xa activity. Once the ACT re...