Point of Care: The Journal of Near-Patient Testing & Technology: March 2008 - Volume 7 - Issue 1 - pp 23-29 doi: 10.1097/POC.0b013e3181635c9b Original Articles Sonoclot Analysis for the Point of Care Diagnosis of Hyperfibrinolysis During Orthotopic Liver Transplantation Biancofiore, Gianni MD*; Bindi, Maria L. MD*; Esposito, Massimo MD*; Bisá, Massimo MD*; Meacci, Luca MD*; Mozzo, Roberto MD*; Urbani, Lucio MD†; Filipponi, Franco† Abstract To properly and effectively manage coagulation disorders during orthotopic liver transplantation, clinicians need reliable and rapid data. From this point of view, the diagnosis of hyperfibrinolysis can be particularly challenging. Among 40 cirrhotic patients consecutively undergoing orthotopic liver transplantation at our center, 11 (27.5%) showed coagulopathy during the surgical procedure. In 5 (45.4%) of them, the Sonoclot analysis diagnosed hyperfibrinolysis (normal onset, rate, and peak but abru...